GATA Transcription Factors and Hematological Diseases
نویسندگان
چکیده
منابع مشابه
Invited Review GATA Transcription Factors and Hematological Diseases
HARIGAE, H. GATA Transcription Factors and Hematological Diseases. Tohoku J. Exp. Med., 2006, 210 (1), 1-9 ── The development of mature blood cells from hematopoietic stem cells is regulated by transcription factors that control and coordinate the expression of lineage-specific genes. The GATA family consists of six transcription factors that function in hematopoietic and endodermal development...
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Previous studies have shown that transcription factors GATA-4 and GATA-6 are expressed in granulosa and thecal cells of the mouse ovary and that GATA-4 expression in ovarian tissue is regulated by gonadotropins. Given the emerging role of GATA-4 and GATA-6 in gonadal cells, we have now studied the expression and regulation of these factors in the mouse testis and testicular cell lines. In situ ...
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Two members of the GATA-binding family of transcription factors, GATA-4 and GATA-6, are expressed in the vertebrate ovary. To gain insight into the role of these factors in ovarian cell differentiation and function, we used in situ hybridization to determine the patterns of expression of GATA-4 and GATA-6 in mouse ovary during development and in response to hormonal stimulation. GATA-4 messenge...
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ژورنال
عنوان ژورنال: The Tohoku Journal of Experimental Medicine
سال: 2006
ISSN: 0040-8727,1349-3329
DOI: 10.1620/tjem.210.1